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<i>Andrographis paniculata<_i> (Burm. F.) Nees

" in MedChemExpress (MCE) Product Catalog:

3699

Inhibitors & Agonists

12

Screening Libraries

167

Fluorescent Dye

124

Biochemical Assay Reagents

289

Peptides

61

MCE Kits

71

Inhibitory Antibodies

650

Natural
Products

637

Recombinant Proteins

119

Isotope-Labeled Compounds

202

Antibodies

43

Click Chemistry

324

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N0677

    Influenza Virus Infection Inflammation/Immunology Cancer
    Dehydroandrographolide succinate, extracted from herbal medicine Andrographis paniculata (Burm f) Nees, is widely used for the treatment of viral pneumonia and viral upper respiratory tract infections because of its immunostimulatory, anti-infective and anti-inflammatory effect .
    Dehydroandrographolide succinate
  • HY-N0677A

    Potassium dehydroandrographolide succinate

    Antibiotic Infection Inflammation/Immunology Cancer
    Kalii Dehydrographolidi Succinas (Potassium dehydroandrographolide succinate), extracted from herbal medicine Andrographis paniculata (Burm f) Nees, is widely used for the treatment of viral pneumonia and viral upper respiratory tract infections because of its immunostimulatory, anti-infective and anti-inflammatory effect .
    Kalii Dehydrographolidi Succinas
  • HY-N2676

    Others Others
    7-O-Methyldihydrowogonin is a flavonoid that can be isolated from Andrographis paniculata .
    7-O-Methyldihydrowogonin
  • HY-N11430

    HIV Infection
    F1839-I is a compound that can be isolated from Stachybotrys. F1839-I has weak cytotoxicity and anti-HIV activity with an IC50 value of 15.6 μM .
    F1839-I
  • HY-149002

    Topoisomerase Apoptosis Cancer
    Topoisomerase I/II inhibitor 4 (compound F16) is a potent topoisomerase I (Topo I) and II (Topo II) dual inhibitor. Topoisomerase I/II inhibitor 4 inhibits cell proliferation, invasion and migration and induces apoptosis. Topoisomerase I/II inhibitor 4 can be used for liver cancer research .
    Topoisomerase I/II inhibitor 4
  • HY-N1492

    Others Others
    14-Deoxy-12-hydroxyandrographolide is a labdane type diterpene compound isolated from the leaves of Andrographis paniculata Nees .
    14-Deoxy-12-hydroxyandrographolide
  • HY-N8614

    Others Others
    Peucedanocoumarin I (compound 1) is a kind of dihydropyranocoumarin. Peucedanocoumarin I can be isolated from the root of f Peucedanum praeruptorum .
    Peucedanocoumarin I
  • HY-147985

    Carbonic Anhydrase Cancer
    hCA I-IN-1 (Compound 6q) is a human carbonic anhydrase I (hCA I) inhibitor with Ki values of 38.3, 716.4, 940.1 and 192.8 nM against hCA I, hCA II, hCAIX and hCAXII, respectively .
    hCA I-IN-1
  • HY-147986

    Carbonic Anhydrase Cancer
    hCA I-IN-2 (Compound 6d) is a selective human carbonic anhydrase I (hCA I) inhibitor with Ki values of 18.8, 375.1, 1721 and 283.9 nM against hCA I, hCA II, hCAIX and hCAXII, respectively .
    hCA I-IN-2
  • HY-156969

    Topoisomerase Btk Cancer
    Topoisomerase I inhibitor 11 is a potent inhibitor of Topoisomerase I. Topoisomerase I inhibitor 11 can bind to BTK .
    Topoisomerase I inhibitor 11
  • HY-162091

    Topoisomerase Cancer
    Topoisomerase I inhibitor 13 (Compound G11) is a Topo I inhibitor that inhibits cancer cell proliferation. Topoisomerase I inhibitor 13 significantly inhibits tumor growth in vivo .
    Topoisomerase I inhibitor 13
  • HY-122949

    DGK Metabolic Disease
    Momordicine I, a triterpenoid compound extracted from momordica charantia L. Momordicine I alleviates isoproterenol-induced cardiomyocyte hypertrophy through suppression of PLA2G6 and DGK-ζ .
    Momordicine I
  • HY-N12370

    Others Others
    Tenaxin I is a component extracted from Radix Scutellariae with neuraminidase inhibitory activity .
    Tenaxin I
  • HY-146437

    Topoisomerase Cancer
    Topoisomerase I inhibitor 6 (Compound 3) is a potent inhibitor of Topoisomerase I. Topoisomerase I inhibitor 6 is able to trap DNA-Top1 cleavage complex and found to be less cytotoxic in non-cancerous cell line. Topoisomerase I inhibitor 6 has the potential for the research of cancer diseases .
    Topoisomerase I inhibitor 6
  • HY-P1032F

    Endogenous Metabolite Endocrinology
    Biotinyl-Angiotensin I (human, mouse, rat) is biotin-labeled Angiotensin I . Angiotensin I (human, mouse, rat) is the precursor to the vasoconstrictor peptide angiotensin II, cleaved by the angiotensin-converting enzyme (ACE) .
    Biotinyl-Angiotensin I (human, mouse, rat)
  • HY-N0676

    Influenza Virus Infection Cancer
    Dehydroandrographolide can be extracted from herbal medicine Andrographis paniculata Nees. Dehydroandrographolide reduces oxidative stress in LPS-induced acute lung injury by inactivating iNOS. Dehydroandrographolide has anti-infective activity .
    Dehydroandrographolide
  • HY-146497

    Topoisomerase Cancer
    Topoisomerase I inhibitor 7 (Compound 8) is a potent inhibitor of Topoisomerase I. Topoisomerase I inhibitor 7 significantly inhibits tumor growth (up to 79%) and increases the lifespan (153%) of mice bearing P388 lymphoma transplants. Topoisomerase I inhibitor 7 indicates prospects for further search of new antitumor agent candidates among the heteroarene-fused anthraquinones .
    Topoisomerase I inhibitor 7
  • HY-N2867

    Others Cancer
    Andrographiside is a labdane diterpenoid glucoside that can be isolated from the leaves of Andrographis paniculata Nees. Andrographiside has antihepatotoxic and antioxidative effects. Andrographiside shows protective effects on mice with hepatotoxicity induced by carbon tetrachloride or tert-butylhydroperoxide (tBHP) .
    Andrographiside
  • HY-150685

    Topoisomerase Prostaglandin Receptor Apoptosis Inflammation/Immunology Cancer
    Topo I/COX-2-IN-1 (1H-30) is a potential Topo I/COX-2 inhibitor. Topo I/COX-2-IN-1 inhibits COX-2 and Topo I with the IC50 value of 0.24 μM and 4.42 μM, respectively. Topo I/COX-2-IN-1 can induce apoptosis and inhibit migration of cancer cells, has anti-cancer activity .
    Topo I/COX-2-IN-1
  • HY-153340

    Keap1-Nrf2 Metabolic Disease
    I-152 is a conjugate containing N-acetyl-cysteine (NAC) and cysteamine (MEA). I-152 activates NRF2 and ATF4 signals. I-152 has anti-proliferative properties .
    I-152
  • HY-E70040

    Endogenous Metabolite Metabolic Disease
    Endoglycoceramidase I (EGCase I) is a glycosidase, is often used in biochemical studies. Endoglycoceramidase I catalyzes a transglycosylation reaction, which transfers the sugar moiety of GSLs to the primary hydroxyl group of several 1-alkanols .
    Endoglycoceramidase I (EGCase I)
  • HY-143265

    Topoisomerase Apoptosis Caspase Cancer
    Topoisomerase I inhibitor 2 (ZML-8) is a highly selective inhibitor of DNA topoisomerase I (Top1). Topoisomerase I inhibitor 2 inhibits Top1 activity and results DNA damage. Topoisomerase I inhibitor 2 blocks G2/M phase and induces apoptosis, exhibits anti-tumor effect .
    Topoisomerase I inhibitor 2
  • HY-P5798

    FAS-I

    Cholinesterase (ChE) Neurological Disease
    Fasciculin-I is isolated from the mambas venom. Fasciculin-I exerts its toxic effects by inhibiting acetylcholinesterase (AChE). Fasciculin-I blocks α-neurotoxins of nicotinic acetylcholine receptors and cardiac toxins that interact with cell membranes .
    Fasciculin-I
  • HY-P2774

    Glo-I

    Others Others
    Glyoxalase I (Glo-I) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    Glyoxalase I
  • HY-131577A

    Dispase I

    Others Others
    Neutral protease I (Dispase I) is a rapid, effective, gentle and neutral protease that can separate intact epidermis from the dermis. Neutral protease I can also separate intact epithelial sheets in culture from the substratum. Neutral protease I preserves the viability of the epithelial cells while cleaving the basement membrane zone region. Neutral protease I can also be used to prevent clumping in suspension cultures. Neutral protease I cleaves fibronectin and type IV collagen, but not laminin, type V collagen, serum albumin, or transferrin .
    Neutral protease I
  • HY-P5179

    HWTX-I

    Calcium Channel Sodium Channel Neurological Disease
    Huwentoxin I (HWTX-I) is a peptide toxin that inhibits voltage-gated sodium channels and N-type calcium channels. Huwentoxin I inhibits sodium channels in rat hippocampus and cockroach dorsal unpaired median (DUM) neurons with IC50 values of 66.1 and 4.80 nM, respectively .
    Huwentoxin I
  • HY-NP072

    MAL I

    Fluorescent Dye Others
    Maackia Amurensis Lectin I (MAL I) is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Maackia Amurensis Lectin I (MAL I) is a biological material or organic compound that can be used in life science research .
    Maackia Amurensis Lectin I
  • HY-NP079

    RCA I

    Fluorescent Dye Others
    Ricinus Communis Agglutinin I (RCA I) is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Ricinus Communis Agglutinin I (RCA I) is a biological material or organic compound that can be used in life science research .
    Ricinus Communis Agglutinin I
  • HY-NP090

    UEA I

    Fluorescent Dye Others
    Ulex Europaeus Agglutinin I (UEA I) is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Ulex Europaeus Agglutinin I (UEA I) is a biological material or organic compound that can be used in life science research .
    Ulex Europaeus Agglutinin I
  • HY-N12073

    MFLNH I

    Others Others
    Monofucosyllacto-N-hexaose I (MFLNH I) is a composition of human milk oligosaccharide .
    Monofucosyllacto-N-hexaose I
  • HY-156723

    Topoisomerase Cancer
    9-Chloromethyl-10-hydroxy-11-F-Camptothecin is a novel camptothecin derivatives. 9-Chloromethyl-10-hydroxy-11-F-Camptothecin is a DNA topoisomerase I (Topo I) inhibitor, can be used in anticancer research .
    9-Chloromethyl-10-hydroxy-11-F-Camptothecin
  • HY-N2013R

    Caspase Apoptosis Inflammation/Immunology
    Aristolactam I (Standard) is the analytical standard of Aristolactam I. This product is intended for research and analytical applications. Aristololactam I (AL-I), is the main metabolite of aristolochic acid I (AA-I), participates in the processes that lead to renal damage. Aristololactam I (AL-I) directly injures renal proximal tubule cells, the cytotoxic potency of AL-I is higher than that of AA-I and that the cytotoxic effects of these molecules are mediated through the induction of apoptosis in a caspase-3-dependent pathway .
    Aristolactam I (Standard)
  • HY-136538

    Survivin Cancer
    LQZ-7I is a survivin-targeting inhibitor. LQZ-7I inhibits survivin dimerization. LQZ-7I orally effectively inhibits xenograft tumor growth and induces survivin loss in tumors .
    LQZ-7I
  • HY-P3055

    DTX-I

    Potassium Channel Neurological Disease Cancer
    Dendrotoxin-I (DTX-I) is a potent K + channels blocker with IC50s of 0.13-50 nM for voltage-gated potassium channel subunits KV1.1, KV1.2 and KV1.6, respectively. Dendrotoxin-I, a neurotoxin, has the potential for cancer research .
    Dendrotoxin-I
  • HY-N11172

    Others Neurological Disease
    Schibitubin I is a lignin. Schibitubin I has neuroprotective activity. Schibitubin I can be isolated from the fruits of Schisandra bicolor var. tuberculata .
    Schibitubin I
  • HY-W035090

    (Trimethylphosphine)gold(I) chloride

    Others
    Chloro(trimethylphosphine)gold(I) ((Trimethylphosphine)gold(I) chloride) is a metal complex with antitumor activity. Chloro(trimethylphosphine)gold(I) has been studied as a potential chemotherapeutic compound in cancer inhibition. Chloro(trimethylphosphine)gold(I) can also be used in organic synthesis reactions as a catalyst to improve reaction efficiency. The biocompatibility of Chloro(trimethylphosphine)gold(I) makes it promising for application in medicine and materials science.
    Chloro(trimethylphosphine)gold(I)
  • HY-E70280

    rEGCase I

    Biochemical Assay Reagents Metabolic Disease
    Recombinant endoglycoceramidase I (rEGCase I) is a glycosidase that catalyzes the hydrolysis of the β-glycosidic linkage between oligosaccharides and ceramides. Recombinant endoglycoceramidase I catalyzes a transglycosylation reaction, which transfers the sugar moiety of glycosphingolipids (GSLs) to the primary hydroxyl group of several 1-alkanols .
    Recombinant endoglycoceramidase I
  • HY-N12727

    Bacterial Infection
    Okaramine I is an Escherichia coli glycosyltransferase (MurG) inhibitor. Okaramine I can be used as an antibacterial agent. Okaramine I can be found in Aspergillus aculeatus .
    Okaramine I
  • HY-NP068

    GSL I

    Fluorescent Dye Others
    Griffonia (Bandeiraea) Simplicifolia Lectin I (GSL I) is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Griffonia (Bandeiraea) Simplicifolia Lectin I (GSL I) is a biological material or organic compound that can be used in life science research .
    Griffonia (Bandeiraea) Simplicifolia Lectin I
  • HY-N12316

    Others Others
    Goshuyuamide-I (compound 4) is a kind of alkaloid. Goshuyuamide-I can be isolated from the fruits of Euodia rutaecarpa. Goshuyuamide-I can be used in the research of analgesics .
    Goshuyuamide I
  • HY-121934

    Others Cancer
    BH3I-2' is the BH3I-2 analogue. BH3I-2 is a Bcl-2 family inhibitor. BH3I-2' can be used for various studies .
    BH3I-2'
  • HY-107301

    Soyasaponin Be; DHS-I

    Potassium Channel Neurological Disease
    Dehydrosoyasaponin I (Soyasaponin Be;DHS-I), a triterpene glycoside, is a potent and reversible calcium-activated potassium (maxi-K) channels activator .
    Dehydrosoyasaponin I
  • HY-P1768

    Uru-TK I

    Bacterial Infection
    Urechistachykinin I (Uru-TK I), an invertebrate tachykinin-related peptides (TRPs) isolated from echiuroid worms, shows antimicrobial activities without a hemolytic effect .
    Urechistachykinin I
  • HY-N0407R

    STAT Inflammation/Immunology
    Picroside I (Standard) is the analytical standard of Picroside I. This product is intended for research and analytical applications. Picroside I is the major ingredient of Picrorhiza scrophulariiflora. Picrorhiza scrophulariiflora is a high value medicinal herb due to rich source of hepatoprotective metabolites, Picroside-I and Picroside-II . Picroside I is a promising agent for the management of asthma. Picroside I reduces the inflammation significantly at its higher dose. Picroside I also downregulates pSTAT6 and GATA3 expressions. Picroside I dose-dependently increases the serum levels of IFN-γ .
    Picroside I (Standard)
  • HY-NP0137

    MAL I (Fluorescein)

    Fluorescent Dye Others
    Maackia Amurensis Lectin I (MAL I) Fluorescein is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Maackia Amurensis Lectin I (MAL I) Fluorescein is a biological material or organic compound that can be used in life science research .
    Maackia Amurensis Lectin I (Fluorescein)
  • HY-NP0141

    RCA I (Fluorescein)

    Fluorescent Dye Others
    Ricinus Communis Agglutinin I (RCA I) Fluorescein is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Ricinus Communis Agglutinin I (RCA I) Fluorescein is a biological material or organic compound that can be used in life science research .
    Ricinus Communis Agglutinin I (Fluorescein)
  • HY-NP0145

    UEA I (Fluorescein)

    Fluorescent Dye Others
    Ulex Europaeus Agglutinin I (UEA I) Fluorescein is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Ulex Europaeus Agglutinin I (UEA I) Fluorescein is a biological material or organic compound that can be used in life science research .
    Ulex Europaeus Agglutinin I (Fluorescein)
  • HY-NP0157

    RCA I (Rhodamine)

    Fluorescent Dye Others
    Ricinus Communis Agglutinin I (RCA I) Rhodamine is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Ricinus Communis Agglutinin I (RCA I) Rhodamine is a biological material or organic compound that can be used in life science research .
    Ricinus Communis Agglutinin I (Rhodamine)
  • HY-NP0158

    UEA I (Rhodamine)

    Fluorescent Dye Others
    Ulex Europaeus Agglutinin I (UEA I) Rhodamine is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Ulex Europaeus Agglutinin I (UEA I) Rhodamine is a biological material or organic compound that can be used in life science research .
    Ulex Europaeus Agglutinin I (Rhodamine)
  • HY-NP0168

    UEA I (Agarose)

    Fluorescent Dye Others
    Ulex Europaeus Agglutinin I (UEA I) Agarose is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Ulex Europaeus Agglutinin I (UEA I) Agarose is a biological material or organic compound that can be used in life science research .
    Ulex Europaeus Agglutinin I (Agarose)

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